Dimitrios Ioannou, PhD

Assistant Professor of Basic Sciences/ Director of Assessment

EDUCATION:

  • PhD – Genetics
  • MPhil – Genetics
  • Bsc Hons – Biology with Biochemistry

BIOGRAPHY:

Dr. Dimitrios Ioannou (he/him/his) joined Roseman University in 2023 as an Assistant Professor for Basic Sciences. His primary role is to develop curriculum around the topics of genetics that will be taught in the medical school. Dr Ioannou brings a multifaceted professional experience through his previous roles in academia, research and clinical embryology. His experience from working in the field of in vitro fertilization has highlighted the importance of inter-professional care and communication between physicians and patients to allow patients to make informed decisions. Dr Ioannou has numerous publications in peer-reviewed journals, books and conference proceedings in the fields of genome organization, genetic basis of infertility and molecular diagnostics.

TEACHING AREAS:

  • Genetics
  • Molecular Biology
  • Clinical Embryology
  • Clinical Diagnostics

RESEARCH INTERESTS:

  • Single cell diagnostics – Preimplantation Genetic Testing platforms
  • Nuclear organization in sperm and preimplantation embryos
  • Genetic basis of infertility

SELECTED PEER-REVIEWED PUBLICATIONS:

  1. Anifandis G, Taylor TH, Messini CI, et al. The Impact of SARS-CoV-2 on Sperm Cryostorage, Theoretical or Real Risk? Medicina (Kaunas). Sep 8 2021;57(9)doi:10.3390/medicina57090946
  2. Ioannou D, Tempest HG. Human Sperm Chromosomes: To Form Hairpin-Loops, Or Not to Form Hairpin-Loops, That Is the Question. Genes (Basel). Jul 3 2019;10(7)doi:10.3390/genes10070504
  3. Ioannou D, Fortun J, Tempest HG. Meiotic nondisjunction and sperm aneuploidy in humans. Reproduction. Jan 2019;157(1):R15-r31. doi:10.1530/rep-18-0318
  4. Ioannou D, Tempest HG. Does genome organization matter in spermatozoa? A refined hypothesis to awaken the silent vessel. Syst Biol Reprod Med. Dec 2018;64(6):518-534. doi:10.1080/19396368.2017.1421278
  5. Ioannou D, Millan NM, Jordan E, Tempest HG. A new model of sperm nuclear architecture following assessment of the organization of centromeres and telomeres in three-dimensions. Sci Rep. Jan 31 2017;7:41585. doi:10.1038/srep41585
  6. Turner K, Fowler K, Fonseka G, Griffin D, Ioannou D. Multicolor detection of every chromosome as a means of detecting mosaicism and nuclear organization in human embryonic nuclei. Panminerva Med. Jun 2016;58(2):175-90.
  7. Ioannou D, Miller D, Griffin DK, Tempest HG. Impact of sperm DNA chromatin in the clinic. J Assist Reprod Genet. Feb 2016;33(2):157-66. doi:10.1007/s10815-015-0624-x
  8. Ioannou D, Tempest HG. Meiotic Nondisjunction: Insights into the Origin and Significance of Aneuploidy in Human Spermatozoa. Adv Exp Med Biol. 2015;868:1-21. doi:10.1007/978-3-319-18881-2_1
  9. Ioannou D, Kandukuri L, Simpson JL, Tempest HG. Chromosome territory repositioning induced by PHA-activation of lymphocytes: A 2D and 3D appraisal. Mol Cytogenet. 2015;8:47. doi:10.1186/s13039-015-0146-3
  10. Ioannou D, Kandukuri L, Quadri A, Becerra V, Simpson JL, Tempest HG. Spatial positioning of all 24 chromosomes in the lymphocytes of six subjects: evidence of reproducible positioning and spatial repositioning following DNA damage with hydrogen peroxide and ultraviolet B. PLoS One. 2015;10(3):e0118886. doi:10.1371/journal.pone.0118886

NCBU COMPLETE BIBLIOGRAPHY LINK:

NCBI complete bibliography

Last updated: 08/14/2023